Optimizing ^177Lu Theranostics Workflows: How Quantek Systems Enhances Personalized Dosimetry

Lutathera administration workflow
Fig. 1. Lutathera administration workflow. Adapted from George et al., “A Single-Institution Experience with 177Lu RPT Workflow Improvements and Qualifying the SPECT/CT Imaging for Dosimetry,” Frontiers in Oncology, vol. 14, 2024, fig. B34.1

In a 2024 study published in Frontiers in Oncology, George et al. described an optimized ^177Lu radiopharmaceutical therapy (RPT) workflow. Their approach integrated patient-specific dosimetry, which improved treatment planning and precision. The team refined imaging alignment, strengthened calibration protocols, and applied structured PDCA (Plan-Do-Check-Act) cycles. As a result, the hybrid SPECT/CT system achieved sub-millimeter registration accuracy—a leap forward in dosimetric quantification.

This precision, supported by end-to-end quality assurance and detailed checklists, signals the future of theranostics. Workflows will become safer, more consistent, and more personalized.

Where Quantek Systems Steps In

George et al. proved that precise dosimetry is possible. However, clinical departments still face the challenge of scaling these workflows in everyday practice.

Quantek Systems addresses this gap with tools that make implementation practical:

  • Automated Task Coordination: Quantek automates PDCA-driven steps with workflows, alerts, and assignment triggers. Teams rely less on manual oversight and save time.
  • Seamless Data Integration: Our platform combines imaging, dosimetry results, and treatment plans into one view. Therefore, oncology teams avoid the delays caused by fragmented data silos.
  • Regulatory & QA Readiness: Built-in audit trails, checklists, and verification steps support safety and compliance. In addition, departments gain confidence that dosimetry workflows meet rigorous standards.
  • Scalable Adaptability: As new theranostic agents or technologies arrive, Quantek’s modular design evolves with them. Thus, workflows like those George et al. developed can extend across multiple sites and modalities.

Why It Matters

The George et al. study demonstrates what is technically possible when hybrid imaging, quality assurance, and dosimetry align. Yet innovation should not stay locked in research environments. Quantek ensures these best practices scale into routine care.

By doing so, departments move beyond “getting by.” Instead, they deliver theranostics with the highest levels of precision and patient-centered care.


Summary Table

Study Insight (George et al., 2024)

How Quantek Systems Complements It
Sub-1 mm SPECT/CT alignment precision Automated workflow tracking and QA reminders
PDCA cycle and detailed checklists Digital, auditable task flows with built-in protocols
Hybrid imaging system calibration and QA Unified data integration, reducing manual steps
Patient-specific dosimetry implementation Scalable deployment with compliance support

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  1. George, Siju C., Ranjini Tolakanahalli, Santiago Aguirre, Taehyung Peter Kim, E. James Jebaseelan Samuel, and Vivek Mishra.
    “A Single-Institution Experience with 177Lu RPT Workflow Improvements and Qualifying the SPECT/CT Imaging for Dosimetry.” Frontiers in Oncology, vol. 14, 2024, fig. B34. PubMed Central, https://pmc.ncbi.nlm.nih.gov/articles/PMC10925616/. ↩︎

 

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